MAY 20TH, 2019, 2:00PM - MAY 25TH, 2019, 2:00PM
The antibody response and the complement system are major effector arms of the immune system. Both have been involved in a plethora of pathological conditions, including autoimmunity, allergy, infections and cancer. Antibodies and complement components regulate, mainly through their receptors (FcR and CR respectively) cell activation, ADCC, ADCP, CDC, CDCP, migration, survival but also, as recently described, metabolism. As the portfolio of antibody—and complement-effector function grow, high-end technological solutions are developed and novel therapeutic applications are proposed.
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The 2nd conference on Antibodies & Complement focused on key advances in both fields with the aim at fostering discussions between antibody experts and complement experts. Some of the critical topics to be covered included:
- antibody & complement (novel) functions
- human antibody repertoires
- complement structure and subcellular localization
- novel technologies
- complement and antibody therapies
After the success of the first edition, this second edition of conference on Antibodies & Complement was again a forum for leaders in the field and new investigators coming from academia, industry and research institutes to discuss where the field is going and what challenges lie ahead.
14:00 Registration
16:30 Welcome & Introductions
Antibodies & Complement I
16:40 Michael Carroll, Harvard Medical School, Massachusetts, USA
Complement in adaptive immunity
17:20 early career
17:40 abstract – oral presentation
17:55 abstract – oral presentation
18:10 Brinda Prasad, Regeneron Pharmaceuticals, New York, USAC1q bispecific antibodies killing bacteria and mammalian cells
19:00 Welcome Reception – Networking
20:00 Dinner
Antibodies & Complement II
09:00 Janine Schuurman, Genmab, Utrecht, The NetherlandsAntibody therapeutics
09:40 early career
10:00 abstract – oral presentation
10:15 abstract – oral presentation
10:30 Coffee break
11:00 Heidi Ling, Imperial College, London, UKComplement in autoimmune diseases
11:40 early career
12:00 abstract – oral presentation
12:15 abstract – oral presentation
12:30 Lunch and social time
Special event for students and postdocs ‘Meet the expert lunch’
15:00 Ron Taylor, University of Virginia, USA
The mechanism of antibody-induced complement-mediated lysis of tumor cells
15:40 early career
16:00 abstract – oral presentation
16:15 Marjolein van Egmond,
VU University Medical Center Amsterdam, The NetherlandsIgA therapeutic antibodies
16:55 abstract – oral presentation
17:10 abstract – oral presentation
17:30 Poster Session I
20:00 Dinner
Antibodies in infectious diseases
09:00 Davide Corti, VIR, Bellinzona, Switzerland
Novel therapeutic antibodies in infectious diseases
09:40 early career
10:00 abstract – oral presentation
10:15 abstract – oral presentation
10:30 Coffee break
11:00 Tineke Cantaert, Institut Pasteur, Phnom Penh, CambodiaProtective antibody response in dengue infections
11:40 abstract – oral presentation
11:55 abstract – oral presentation
12:10 Taia Wang, Stanford University, USAFucosylation on anti-dengue antibodies
12:50 Lunch and social time
18:00 Christian Busse, German Cancer Research Center, Heidelberg, Germany
Anti-malaria Abs and repertoires analysis
18:40 abstract – oral presentation
18:55 abstract – oral presentation
19:10 Florian Krammer, Icahn School of Medicine at Mount Sinai, New York, USAAnti-influenza antibody repertories
20:00 Dinner
Complement
09:00 Piet Gros, Utrecht University, The NetherlandsAntibody and complement structures
09:40 early career
10:00 abstract – oral presentation
10:15 abstract – oral presentation
10:30 Coffee break
11:00 Daniel Ricklin, University Basel, SwitzerlandComplement inhibitors
11:40 early career
12:00 abstract – oral presentation
12:15 abstract – oral presentation
12:30 Lunch and social time
Special event for students and postdocs ‘Meet the expert lunch’15:00 Doryen Bubeck, Imperial College, London, UK
Cryo-EM structures of MAC
15:40 Claudia Kemper, National Institutes of Health, Bethesda, USAIntracellular complement
16:20 early career
16:40 Franscesco Tedesco, University of Trieste, Italy
Alternative roles of C1q in cancer and migration
17:30 Poster Session II
20:00 Dinner
Antibody features
09:00 Sarel J. Fleishman, Weizmann Institute, IsraelComputational design of antibodies
09:40 early career
10:00 abstract – oral presentation
10:15 abstract – oral presentation
10:30 Coffee break
11:00 Andrea van Elsas, Aduro Biotech Europe, Oss, The NetherlandsNext generation antibodies
11:40 abstract – oral presentation
11:55 abstract – oral presentation
12:10 Brian Sutton, King’s College London, UK
IgE, allergens, auto-antibodies and antigen recognition
12:50 Lunch and social time
18:00 Dario Neri, Philogen, Sovicille, Italy Antibodies armed with cytokines
18:40 Brandon de Kosky, Kansas University, USAYeast display platform
19:20 Michel Cogné, University of Limoges, FranceIgG5, the new human IgG subclass
20:00 Dinner
22:00 Social entertainment
Saturday, May 25, 2019 Departure
Confirmed speakers
Doryen Bubeck, Imperial College, London, UK
Christian Busse, German Cancer Research Center, Heidelberg, Germany
Tineke Cantaert, Institut Pasteur, Phnom Penh, Cambodia
Michael Carroll, Harvard Medical School, Massachusetts, USA
Michel Cogné, University of Limoges, France
Davide Corti, VIR, Bellinzona, Switzerland
Brandon de Kosky, Kansas University, USA
Sarel J. Fleishman, Weizmann Institute, Israel
Piet Gros, University Utrecht, The Netherlands
Claudia Kemper, National Institutes of Health, Bethesda, USA
Florian Krammer, Icahn School of Medicine at Mount Sinai, New York, USA
Heidi Ling, Imperial College, London, UK
Dario Neri, Philogen, Sovicille, Italy
Brinda Prasad, Regeneron Pharmaceuticals, New York, USA
Daniel Ricklin, University Basel, Switzerland
Janine Schuurman, Genmab, Copenhagen, Denmark
Brian Sutton, King´s College London, UK
Ron Taylor, University of Virginia, USA
Francesco Tedesco, University of Trieste, Italy
Marjolein van Egmond, VU University Medical Center Amsterdam, The Netherlands
Andrea van Elsas, Aduro Biotech Europe, Oss, The Netherlands
Taia Wang, Stanford University, USA
Information about the place
Venue
Hotel Eden Roc – Punta de Port Salvi, s/n
17220 Sant Feliu de Guíxols Girona – Spain
Time
May 20th, 2019, 2:00pm – May 25th, 2019, 2:00pm
Catering
Coffee breaks; lunch and dinner buffet
Hashtag
#AntibodiesComplement19
Registration
Registration deadline: April 22nd, 2019
- 800 € – Scientist (single room)
- 700 € – Scientist (double room)
- 650 € – Student (double room, for single room register as scientist)
- 1000 € – Industry (single room)
- 320 € – Accompanying quest (non participation)
The registration fee includes:
- 5 nights at the Eden Roc Hotel (regardless of the registration status)
- admission to all scientific sessions and poster exhibition
- conference materials
- internet access
- breakfast, lunch, dinner, coffee breaks and refreshments
- social entertainment
Please note accompanying persons are not eligible to participate at the conference.
Abstract submission
Abstract deadline: April 4th, 2019
We invite all registered participants to submit an abstract about their research. The scientific organizing committee will review all abstracts and select the most relevant contributions for short talks or poster presentation. Abstracts can only be submitted online via the “Register now” button.
Travel grants
Multiple travel grants (€500-€650) were awarded to selected students and postdocs. Selection was be performed by the conference organizers and session chairs.
Requirements :
1. submit an abstract
2. request financial support including a support letter from your mentor
3. register for free at The Antibody Society
Organizers
Pierre Bruhns
Institut Pasteur, Paris, France
Falk Nimmerjahn
University of Erlangen-Nuernberg, Germany
Suzan H.M. Rooijakkers
University Medical Center Utrecht,
The Netherlands
Kathrin de la Rosa
Max Delbrück Center for Molecular Medicine in the Helmholtz Association
Berlin, Germany